Low Testosterone And Type 1 Diabetes: What Correlations Are There?

Low Testosterone And Type 1 Diabetes: What Correlations Are There?

Research suggests that there is a significant correlation between low testosterone levels and Type 1 diabetes in men. Several studies have highlighted this association, shedding light on the underlying mechanisms:

Insulin Resistance:

Type 1 diabetes is characterized by insulin deficiency, leading to increased insulin resistance. Insulin resistance, in turn, can contribute to lower testosterone levels. Insulin resistance interferes with the production of sex hormone-binding globulin (SHBG), a protein that binds to testosterone in the blood. As SHBG levels decrease, the amount of free testosterone available for use in the body also decreases.


Obesity is a common risk factor for both Type 1 diabetes and low testosterone levels. Excess body weight and abdominal fat accumulation can lead to insulin resistance and hormonal imbalances, including reduced testosterone production.


Individuals with Type 1 diabetes often experience episodes of hypoglycemia, where blood sugar levels drop below normal. Hypoglycemia can have negative effects on testosterone production, potentially contributing to low testosterone levels.

Oxidative Stress:

Type 1 diabetes is associated with increased oxidative stress, which can impact Leydig cell function in the testes. Leydig cells are responsible for testosterone production, and oxidative stress can disrupt their normal activity, leading to reduced testosterone levels.

Chronic Inflammation:

Inflammation is a common feature of Type 1 diabetes, and chronic inflammation can negatively impact testosterone production. Inflammatory cytokines interfere with the Leydig cells’ ability to produce testosterone, further contributing to low testosterone levels.

So What Do I Do If I Suspect An Issue With Testosterone Levels?

If you suspect that you have an issue with testosterone levels, it is essential to take proactive steps and seek appropriate medical guidance. Our clinic is the perfect resource to help you navigate your diabetes concerns as well as your hormones. Dr. Timothy Graham, MD, and the other knowledgeable providers in our office will help you in your wellness journey! We have an onsite lab where once you meet with a provider, you can have labs drawn the same day and we will follow you with the appropriate course of treatment.

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Additional Resources:
Look for further information on our website: www.DETSutah.com

PubMed is a widely used database of scientific literature. By searching for keywords such as “low testosterone and Type 1 diabetes,” you can find relevant research articles and studies on the topic. Access PubMed at: www.ncbi.nlm.nih.gov/pubmed.

American Diabetes Association is always a good resource for anyone concerned about managing Diabetes https://diabetes.org/healthy-living/sexual-health